Ferroptosis-centered Drug Response Information
General Information of the Drug (ID: ferrodrug0396)
| Name |
Huaiqihuang
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|---|---|---|---|---|---|
| Drug Type |
Traditional Chinese Medicin
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Full List of Ferroptosis Target Related to This Drug
Unspecific Target
| In total 1 item(s) under this Target | ||||
| Experiment 1 Reporting the Ferroptosis-centered Drug Act on This Target | [1] | |||
| Responsed Disease | Chronic kidney disease | ICD-11: GB61 | ||
| Pathway Response | Apoptosis | hsa04210 | ||
| Autophagy | hsa04140 | |||
| Ferroptosis | hsa04216 | |||
| Necroptosis | hsa04217 | |||
| Cell Process | Cell apoptosis | |||
| Cell autophagy | ||||
| Cell ferroptosis | ||||
| Cell pyroptosis | ||||
| Cell clockophagy | ||||
| Response regulation | Huaiqihuang has an adjuvant therapeutic effect on kidney disease and even a variety of cancers. Its mechanism includes regulation of oxidative stress, immunity, autophagy, apoptosis, ferroptosis, and pyroptosis. In various kinds of kidney system-related diseases, HQH can effectively reduce hematuria and proteinuria, protect podocytes, regulate cell death, and other functions. The aim is to provide new ideas for the treatment of clinical nephropathy. | |||