General Information of the Drug (ID: ferrodrug0389)
Name
Eucommia ulmoides Oliver-Tribulus terrestrisL
Drug Type
Small molecule
Full List of Ferroptosis Target Related to This Drug
Unspecific Target
In total 1 item(s) under this Target
Experiment 1 Reporting the Ferroptosis-centered Drug Act on This Target [1]
Responsed Disease Essential hypertension ICD-11: BA00
Pathway Response Ferroptosis hsa04216
Cell Process Cell ferroptosis
Response regulation The active ingredients of Eucommia ulmoides Oliver-Tribulus terrestrisL (EUO-TT) drug pair may act on proteins associated with the neuroactive ligand-receptor interaction pathway to regulate ferroptosis in vascular neurons cells, ultimately affecting the onset and progression of hypertension.
References
Ref 1 Eucommia ulmoides Oliver-Tribulus terrestris L. Drug Pair Regulates Ferroptosis by Mediating the Neurovascular-Related Ligand-Receptor Interaction Pathway- A Potential Drug Pair for Treatment Hypertension and Prevention Ischemic Stroke. Front Neurol. 2022 Mar 8;13:833922. doi: 10.3389/fneur.2022.833922. eCollection 2022.