Ferroptosis-centered Drug Response Information
General Information of the Drug (ID: ferrodrug0030)
| Name |
Sodium Chlorate
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| Synonyms |
SODIUM CHLORATE; 7775-09-9; Chloric acid, sodium salt; Asex; Atlacide; Agrosan; Desolet; Oxycil; Sodakem; Travex; Evau-super; Kusa-tohru; B-Herbatox; Granex O; Shed-A-leaf; Chlorate de sodium; Chlorsaure; Kusatol; Rasikal; Tumbleaf; Tumbleleaf; Dervan; Defol; Fall; Drexel defol; Harvest-aid; Soda chlorate; VAL-DROP; Weed Killer; Chlorate salt of sodium; Drop-Leaf; Hibar C; Leafex 2; Leafex 3; Sodium chlorate (NaClO3); Caswell No. 753; Ortho-C-1-Defoliant; Natriumchloraat; Natriumchlorat; Sodium chlorate [ISO]; Natrium chlorat; Natrium chloraat; Grain sorghum harvest-aid; T95DR77GMR; Shed-A-Leaf L; Sodium(chlorate de); Sodio (clorato di); CCRIS 9185; HSDB 732; DTXSID7026025; Sodium (chlorate de); CHEBI:65242; United Chemical Defoliant No. 1; NACLO3; Ortho C-1 defoliant & weed killer; EINECS 231-887-4; UNII-T95DR77GMR; EPA Pesticide Chemical Code 073301; DTXCID206025; Chloric acid, sodium salt (1:1); 9011-70-5; EC 231-887-4; SODIUM CHLORATE (II); SODIUM CHLORATE [II]; SODIUM CHLORATE (MART.); SODIUM CHLORATE [MART.]; MFCD00003479; Chlorsaure [German]; Natriumchloraat [Dutch]; Natriumchlorat [German]; Natrium chloraat [Dutch]; Natrium chlorat [German]; Dropleaf; sodium;chlorate; Sodium(chlorate de) [French]; Sodio (clorato di) [Italian]; Sodium (chlorate de) [French]; Chlorate de sodium [ISO-French]; UN1495; UN2428; Sodium chlorate [UN1495] [Oxidizer]; CHLORATE OF SODA; SHED-A-LEAF'L'; SODIUM CHLORATE [MI]; Pesticide Code: 073301.; SODIUM CHLORATE [HSDB]; SODIUM CHLORATE [INCI]; CHEMBL1559268; SODIUM CHLORATE [WHO-DD]; YZHUMGUJCQRKBT-UHFFFAOYSA-M; NSC41881; Tox21_202133; NSC-41881; AKOS015843818; SODA CHLORIC ACID, SODIUM SALT; UNITED CHEMICAL DEFOLIANT NO 1; NCGC00091465-01; NCGC00259682-01; CAS-7775-09-9; Sodium chlorate, ACS reagent, >=99.0%; Sodium chlorate, ReagentPlus(R), >=99%; Sodium chlorate, p.a., ACS reagent, 99%; 3-(4-ISOBUTYL-PHENYL)-PROPIONICACID; FT-0694099; Sodium chlorate, SAJ first grade, >=98.0%; C18765; Q407446; Sodium chlorate, puriss. p.a., >=99.0% (T); Sodium chlorate - metastable high temperature (255C) phase III
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| Structure |
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3D MOL
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| Formula |
ClNaO3
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| IUPAC Name |
sodium;chlorate
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| Canonical SMILES |
[O-]Cl(=O)=O.[Na+]
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| InChI |
InChI=1S/ClHO3.Na/c2-1(3)4;/h(H,2,3,4);/q;+1/p-1
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| InChIKey |
YZHUMGUJCQRKBT-UHFFFAOYSA-M
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| PubChem CID | |||||
Full List of Ferroptosis Target Related to This Drug
Unspecific Target
| In total 1 item(s) under this Target | ||||
| Experiment 1 Reporting the Ferroptosis-centered Drug Act on This Target | [1] | |||
| Responsed Disease | Health | ICD-11: N.A. | ||
| Pathway Response | Fatty acid metabolism | hsa01212 | ||
| Ferroptosis | hsa04216 | |||
| Cell Process | Cell ferroptosis | |||
| In Vitro Model | HT22 cells | Normal | Mus musculus | CVCL_0321 |
| Response regulation | The widely used sulfation inhibitor sodium chlorate and b-d-xyloside, which prevents proteoglycan glycosaminoglycan chain attachment, both reduced HS and CS, and exacerbated glutamate- and erastin-induced cell death, suggesting that extracellular matrix influenced oxytosis and ferroptosis. | |||